Advanced Age as a Risk Factor of Drug-Induced Diseases

Periodontal Diseases as a Risk Factor

AGE proteins as a causative factor in Alzheimer's Disease

The reaction between reducing sugars and protein free amines, known as the Maillar reaction results in the formation of advanced glycation endproducts (AGEs). AGE modification changes the structure of proteins to amyloid cross-beta structure. These protein structures can activate receptors known as RAGE on glial cells (microglia and astrocytes), and induce the expression of inducible nitric oxi...

AGE proteins as a causative factor in Alzheimer's Disease

The reaction between reducing sugars and protein free amines, known as the Maillar reaction results in the formation of advanced glycation endproducts (AGEs). AGE modification changes the structure of proteins to amyloid cross-beta structure. These protein structures can activate receptors known as RAGE on glial cells (microglia and astrocytes), and induce the expression of inducible nitric oxi...

Ethnic background as a risk factor for advanced age-related macular degeneration in Israel.

BACKGROUND Age-related macular degeneration is the most common cause of legal blindness in the developed world including Israel. Ethnic background is a risk factor for advanced AMD in several populations, however the relative prevalence of this disease in different ethnic groups in the Middle East is unknown. OBJECTIVES To compare the prevalence of advanced AMD in Arabs and Jews in Israel. ...

Sedentary behaviour as a risk factor for cardiovascular diseases in pediatric age

The term “sedentary” has historically been used to refer to individuals with low physical activity levels or not meeting some criterion level of physical activity. According to the recent findings, sedentary behaviour has been defined not simply as the absence of moderate-to-vigorous physical activity, but as a class of behaviours (e.g. sitting, watching TV or playing video games) characterized...